Meiosis is a specialized type of cell division that produces gametes (sex cells) with half the number of chromosomes as the parent cell. Genetic variation in gametes arises from two key processes during meiosis: crossing over and independent assortment.
Crossing Over: During prophase I of meiosis, homologous chromosomes (pairs of chromosomes with genes for the same traits) pair up in a process called synapsis. While paired, non-sister chromatids (one from each homologous chromosome) exchange genetic material at points called chiasmata. This exchange of DNA is called crossing over. Crossing over results in a recombinant chromosome, which contains a mixture of alleles from the maternal and paternal chromosomes. This creates new combinations of alleles on the same chromosome, leading to genetic diversity. For example, a chromosome might have a combination of alleles inherited from the mother and father that were not present in either parent.
Independent Assortment: During metaphase I of meiosis, homologous chromosome pairs line up randomly at the metaphase plate. The orientation of each pair is independent of the orientation of other pairs. This means that the maternal and paternal chromosomes are randomly distributed to the daughter cells. Since there are 2n possible combinations of maternal and paternal chromosomes (where 'n' is the haploid number of chromosomes), this leads to a vast number of possible gamete combinations. For example, in humans (n=23), there are 223 = 8,388,608 different possible combinations of chromosomes in a gamete.
Therefore, the combination of crossing over and independent assortment ensures that each gamete receives a unique combination of alleles, resulting in genetically diverse offspring. This is crucial for evolution, as it provides the raw material for natural selection to act upon.