Phenotypic variation, the difference in observable characteristics between individuals, can be significantly influenced by genetic factors. This arises from the diverse combinations of alleles an individual inherits from their parents. Alleles are different versions of a gene, and the specific combination of alleles an individual possesses determines their genotype. This genotype, in turn, dictates their phenotype.
Allele combinations lead to variation because different combinations of alleles can produce different phenotypes. For example, consider the gene for flower colour in pea plants. If a plant inherits two alleles for purple flowers (PP), it will have a purple phenotype. If it inherits one allele for purple (P) and one for white (p) (Pp), it will have a purple phenotype because purple is dominant. However, if it inherits two alleles for white flowers (pp), it will have a white phenotype. The different allele combinations (PP, Pp, pp) result in distinct phenotypes.
Dominance is a key concept in understanding how genetic factors influence phenotype. A dominant allele will mask the expression of a recessive allele when present. Consider the gene for cystic fibrosis. Individuals with two recessive alleles (cc) will have cystic fibrosis. Individuals with one dominant allele (C) and one recessive allele (c) (Cc) will be carriers but will not have the disease. Individuals with two dominant alleles (CC) will not have cystic fibrosis. This demonstrates how the dominance relationship between alleles directly impacts the observable phenotype.
Incomplete dominance provides another example of genetic influence. In incomplete dominance, neither allele is completely dominant over the other. For instance, in snapdragons, a cross between a homozygous red-flowered plant (RR) and a homozygous white-flowered plant (rr) will produce offspring with pink flowers (Rr). The pink phenotype is an intermediate phenotype resulting from the blending of the two alleles. This shows how the interaction of alleles at a single gene locus can lead to a range of phenotypic expressions.
In summary, genetic factors, through the interplay of allele combinations, dominance relationships, and incomplete dominance, are fundamental determinants of phenotypic variation. The specific alleles an individual inherits and how they interact dictate the observable traits.